The risk of having frequent symptoms increased by more than two-fold in women whose BMI increased by more than 3.5 kg/m 2 (OR 2.29, CI 1.84 to 2.86). In this case-control study, women who reduced their BMI by 3.5 kg/m 2 had nearly a 40% reduced risk of reflux symptoms (at least once a week) compared with women whose BMI did not change (OR 0.64, 95% CI 0.42 to 0.97). Body-mass index and symptoms of gastroesophageal reflux in women. Sleep disturbance improved in 13/20 (65%) patients following elevation of the bed head. In this small study, which was conducted among people with nocturnal reflux symptoms, compared with no bed head elevation at baseline, elevation of the bed head by 20 cm led to improvements at day 7 in mean supine reflux time (15.0% ± 8.4 vs 13.7% ± 7.2 p = 0.001), mean acid clearance time (3.8 min ± 2.0 vs 3.0 min ± 1.6, p = 0.001) and mean number of reflux episodes 5 minutes or longer (3.3 ± 2.2 vs 1.0 ± 1.2 p = 0.001). Effect of bed head elevation during sleep in symptomatic patients of nocturnal gastroesophageal reflux. In this prospective cohort study, among people who were overweight or obese, an average weight loss of 13.1 kg from baseline was associated with a significant reduction in reflux symptoms (15% vs 37% p <0.01). Weight loss can lead to resolution of gastroesophageal reflux disease symptoms: a prospective intervention trial. There was a was dose-dependent association between weight loss and improved reflux symptoms (p <0.001). The corresponding odds increased four-fold among people taking antireflux medicines at least weekly (OR 3.95, 95% CI 2.03 to 7.65). In this large, prospective, population-based cohort study, among people taking no or less than weekly antireflux medicines, there was a two-fold improvement in reflux symptoms following a >3.5 kg/m 2 decrease in BMI compared with a <0.5 kg/m 2 change (OR 1.98, 95% CI 1.45 to 2.72). A prospective population-based cohort study: the HUNT study. Weight loss and reduction in gastroesophageal reflux. The improvement was seen in people with a normal BMI taking an antacid at least weekly. In this large, prospective, population-based cohort study, people who stopped smoking had an almost two-fold improvement in severe reflux symptoms (adjusted odds ratio 1.78, 95% confidence interval 1.07 to 2.97) compared with people who continued to smoke. A prospective population-based cohort study: the HUNT Study. Tobacco smoking cessation and improved gastroesophageal reflux. There was good evidence that weight reduction and stopping smoking could reduce symptoms of GORD. In this systematic review, an association was found between smoking and high body mass index (BMI) and gastro-oesophageal reflux disease (GORD). Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations. It aligns with Australian recommendations. #Gord vs gerd updateThis update includes information on GORD complications, diagnosis and management. #Gord vs gerd professionalThe Best Practice Advocacy Centre New Zealand (bpac nz) is an independent, not-for-profit organisation that aims to deliver educational and continuing professional development programs to medical practitioners and other health professionals throughout New Zealand. It also makes detailed recommendations on Helicobacter pylori eradication.īpac NZ 2014 update on the management of GORD It covers the investigation and management of GORD and dyspepsia in people aged 18 and over. The Gastrointestinal drugs chapter of the Australian Medicines Handbook has a section on GORD.Ĭlinical guideline CG184 was developed by the National Institute for Health and Care Excellence (NICE) in the UK. It is the fifth edition of these guidelines, and was initially planned to be updated again in 2013/2014.Īustralian Medicines Handbook: Gastrointestinal drugs This clinical update on the diagnosis and management of GORD was published by the Digestive Health Foundation and sponsored by the Gastroenterological Society of Australia (GESA). The Gastrointestinal Guidelines of eTG complete have a chapter on disorders of the oesophagus, which includes detailed information about gastro-oesophageal reflux and GORD, as well as medicines recommended to treat these conditions.
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